Arterra was founded in 2004 by Dr. Gabriella Colucci upon her return to Italy after 10 years of research experience at University California San Diego and Arena Pharmaceuticals.

In January 2005 Isagro SpA, an Italian agrochemical company, acquired 22% stake of Arterra Bioscience. Since then, the two companies have been in a long-term agreement.

In May 2008 Arterra subscribed a research contract with Intercos SpA, one of the leading worldwide operators in the creation, development and production of make up for the cosmetic industry.

In 2010 Arterra Bioscience and Intercos Group founded Vitalab srl, a joint-venture focused on the commercialization of innovative active ingredients for skin care, personal care and functional make up.