publications

2021

Ceccacci S, De Lucia A, Tito A, Tortora A, Falanga D, Arciello S, Ausanio G, Di Cicco C, Monti MC and Apone F.
An Oenothera biennia Cell Cultures Extract Endowed with Skin Anti-Ageing Activity Improves Cell Mechanical Properties.
Metabolites 2021, 11, 527. https://doi.org/10.3390/metabo11080527.

Apone F.
Uses and Properties of Bioactive Peptides in Skin Care.
HPC Today, vol. 16 (3), 2021.

Tito A, Colantuono A, Pirone L, Pedone E, Intartaglia D, Giamundo G, Conte I, Vitaglione P, Apone F.
Pomegranate Peel Extract as an Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 Receptor (in vitro): A Promising Source of Novel Antiviral Drugs.
Front Chem. 2021 Apr 28;9:638187.

Dini I, Falanga D, Di Lorenzo R, Tito A, Carotenuto G , Zappelli C, Grumetto L , Sacchi A, Laneri S, Apone F.
An Extract from Ficus carica Cell Cultures Works as an Anti-Stress Ingredient for the Skin.
Antioxidants2021, 10, 515. https://doi.org/10.3390/antiox10040515.

Tortora A, Bimonte M, Tito A, Zappelli C, Apone F.
Soothing Moves: Cannabis sativa Cell Culture Alleviates Inflammation. 
Cosmetic & Toiletries, Jan 2021, vol. 136, n. 1, 34-39.

2020

Laneri S, Dini I, Tito A, Di Lorenzo R, Bimonte M, Tortora A, Zappelli C, Angelillo M, Bernardi A, Sacchi A, Colucci MG and Apone F.
Plant Cell Culture Extract of Cirsium eriophorum with Skin Pore Refiner Activity by Modulating Sebum Production and Inflammatory Response.
Phytother Res. 2020; 10.1002/ptr.6832. doi: 10.1002/ptr.6832.

Tito A, Tortora A, De Lucia A, Zappelli C, Colucci MG and Apone F.
A Peptide Preparation from Scabiosa arvensis Cell Cultures Increases Skin Compactness by Stimulating Collagen XVII and Insulin-like Growth Factor.
The Proceedings of the 26th IFSCC Congress 2020, Yokohama.

Tito A, Colantuono A, Pirone L, Pedone E, Intartaglia D, Giamundo G, Conte I, Vitaglione P and Apone F.
A Pomegranate Peel Extract as Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 (in vitro): A Promising Source of Novel Antiviral Drugs.
bioRxiv December 2020, https://doi.org/10.1101/2020.12.01.406116.

Apone F, Tito A, Arciello S, Carotenuto G and Colucci MG.
Plant Tissue Cultures as Sources of Ingredients for Skin Care Applications.
Annual Plant Reviews 2020, 3: 135-150. 

Tito A, Minale M, Riccio S, Grieco F, Colucci MG and Apone F.
A Triticum vulgare Extract Exhibits Regenerating Activity during the Wound Healing Process.
Clin Cosm & Invest Dermatol 2020, 13: 21-30.

Tito A, Zappelli C, Angelillo M, Colucci MG and Apone F.
A New Ingredient from Rosa rugosa Tissue Cultures Delays Skin Aging by Promoting Mitochondrial Functions.
Personal Care Europe 2020, April 131-137.

2019

Tito A, Carola A, Bertelli G, Rando P, Nohynek L, Oksman-Caldentey KM, Rischer H, Zappelli C, Colucci MG, Apone F.
A Rubus arcticus derived ingredient stimulates immune defence and reduces inflammation in skin cells by promoting microbiota balance.
The Proceedings of the 25th IFSCC Conference 2019, Milan.

Bimonte M, Carola A, Barbulova A, Zappelli C, Angelillo M, Cucchiara M, Apone F and Colucci MG.
Aubergine mutes TRPV1 and boosts TRPV-3 and TRPV-4 to reinforce and comfort skin (2019).
Cosmetics & Toiletries, 134, n. 9, 50-61.

Palmieri G, Arciello S, Bimonte M, Carola A, Tito A, Gogliettino M, Cocca E, Fusco C, Balestrieri M, Colucci MG, Apone F.
The extraordinary resistance to UV radiations of a manganese Superoxide Dismutase of Deinococcus radiodurans offers promising potentialities in skin care applications.
J Biotechnol. 2019, 302: 101-111.

Apone F, Barbulova A, Colucci MG.
Plant and Microalgae Derived Peptides Are Advantageously Employed as Bioactive Compounds in Cosmetics.
Front. In Plant Sci., 12 June 2019 doi: 10.3389/fpls.2019.00756

Tito A, Barbulova A, Zappelli C, Leone M, Ruvo M, Mercurio FA, Chambery A, Russo R, Colucci MG & Apone F.
The Growth Differentiation Factor 11 is involved in skin fibroblast ageing and is induced by a preparation of peptides and sugars derived from plant cell cultures.
Mol Biotechnol. 2019 Mar;61(3):209-220.

2018

Guerriero G, Berni R, Muñoz-Sanchez JA, Apone F, Abdel-Salam EM, Qahtan AA, Alatar AA, Cantini C, Cai G, Hausman JF, Siddiqui KS, Hernández-Sotomayor SMT, Faisal M.
Production of Plant Secondary Metabolites: Examples, Tips and Suggestions for Biotechnologists.
Genes (Basel). 2018 Jun 20; 9(6).

Bimonte M, Carola A, Tito A, Barbulova A, De Lucia A, Del Piaz F, Apone F & Colucci MG.
Plant cell cultures of Daphne odora produce compounds that help fighting cold stress in the skin.
Cosmetics & Toiletries, 133, n.1, 34-51.

De Lucia A, Zappelli C, Angelillo M, Langellotti AL, Fogliano V, Cucchiara M, Colucci MG, Apone F.
A novel biotechnological active ingredient, derived from the microalga Spirulina, increases hydration and reduces osmotic stress in skin cells.

H&PC Today – Household and Personal Care Today – vol. 13(4) July/August 2018.

D’Antuono I, Carola A,  Sena LM, Linsalata V, Cardinali A, Logrieco AF, Colucci MG and Apone F.
Artichoke polyphenols produce skin anti-age effects by improving endothelial cell integrity and functionality.
Molecules 2018, 23, 2729; doi:10.3390/molecules23112729.

Apone F, Zappelli C, Angelillo M & Colucci MG.
Biotechnology research to obtain safe, effective and sustainable ingredients for Cosmetics (in polish).
Chem & Business, 4/2018: 76-81.

2017

Sandomenico A, Severino V, Apone F, De Lucia A, Caporale A, Dotia N, Russo A, Russo R, Rega C, Del Giacco T, Falcigno L, Ruvo M, Chambery A.
Trifluoroacetylated tyrosine-rich D-tetrapeptides have potentantioxidant activity.
Peptides, 89: 50–59.

Apone F, Barbulova A, Zappelli C, Colucci MG.
Green biotechnology in cosmetics: using plant cell cultures as sources of active ingredients.
HPC Today, vol. 12 (3), May/June 2017.

Sena LM, Zappelli C, Apone F, Barbulova A, Tito A, Leone A, Oliviero T, Ferracane R, Fogliano V, Colucci MG.
Brassica rapa hairy root extracts promote skin depigmentation by modulating melanin production and distribution.
J Cosmet Dermatol.1–12.

Squillaci G, Apone F, Sena LM, Carola A, Tito A, Bimonte M, De Lucia A, Colucci MG, LA Cara F, Morena A.
Chestnut (Castanea sativa Mill.) industrial wastes as a valued bioresource for the production of active ingredients.
Process Biochemistry, http://dx.doi.org/10.1016/j.procbio.2017.09.017.

Di Martino O, Tito A, De Lucia A, Cimmino A, Cicotti F, Apone F, Colucci MG and Calabrò V.
Hibiscus syriacus Extract from an Established Cell Culture Stimulates Skin Wound Healing.
BioMed Res Inter, Article ID 7932019, 9 pages, https://doi.org/10.1155/2017/7932019.

2016

Imparato G, Casale C, Scaramella S, UrciuoloF, Bimonte M, Apone F, Colucci MG and Netti PA.
A novel engineered dermis for in vitro photodamage research.
J Tissue Eng Regen Med. 2016 Feb 8.

Bimonte M, De Lucia A, Carola A, Tito A, Buono S, Langellotti AL, Fogliano V, Colucci MG and Apone F.
Galdieria sulphuraria Relieves Oily and Seborrheic Skin By Inhibiting the 5-α Reductase Expression in Skin Cells and Reducing Sebum Production In Vivo.

Trichology and Cosmetology. Volume 1, tissue 1.

Rogato A, Valkov VT, Alves LM, Apone F, Colucci MG, Chiurazzi M.
Down-regulated Lotus japonicus GCR1 plants exhibit nodulation signalling pathways alteration.
Plant Sci., 247: 71-82.

Zappelli C, Barbulova A, Apone F, Colucci MG.
Effective Active ingredients obtained through Biotechnology.
Cosmetics, 3, 39.

Zappelli C, Ciccotti F, Tito A, Carola A, De Lucia A, Sena LM, Tortora A, Bimonte M, Cucchiara M, Apone F, Colucci MG.
Perking Up Skin: Green Coffee Promotes Barrier Recovery, Turn Over and Lightening.
Cosmetics & Toiletries, 132, n.1, 24-36.

2015

Barbulova A, Apone F & Colucci MG.
New Trends in Cosmetics: By-Products of Plant Origin and Their Potential Use as Cosmetic Active Ingredients.
Cosmetics, 2, 82-92.

Tito A, Bimonte M, Carola A, De Lucia A, Barbulova A, Tortora A, Colucci MG & Apone F.
An oil-soluble extract of Rubus idaeus cells enhances hydration and water homeostasis in skin cells.

Int. J. Cosmet. Sci., 2015 May 4. doi: 10.1111/ics.12236.

2014

Barbulova A, Apone F & Colucci MG.
Plant Cell Cultures as Source of Cosmetic Active Ingredients.

Cosmetics, 1, 94-104.A.

Apone F, Ruggiero A, Tortora A, Tito A, Grimaldi MR, Arciello S, Andrenacci D, Di Lelio I & Colucci MG.
Targeting the diuretic hormone receptor to control the cotton leafworm, Spodoptera littoralis.

Journal of Insect Science, Vol. 14, 87, 1-16.

Bimonte M, Tito A, Carola A, Barbulova A, Hill J, Cucchiara M, Apone F & Colucci MG.
Dolichos cell culture extract for protection against UV damage.
Cosmetics & Toiletries, 129, 46-56.

2012

Tortora A, Arciello S, Colucci MG, Apone F.
Identification of Novel Compounds or Mixtures, Activating Common Defense Responses to Abiotic Stress both in Plants and Mammalian Skin Cells.

Advances in Medicine and Biology, vol. 49, pp. 47-67.

Buono S, Langellotti A, Martello A, Bimonte M, Tito A, Carola A, Apone F, Colucci MG, Fogliano V.
Biological Activities of Dermatological Interest by the Water Extract of the Microalga Botryococcus braunii.

Arch Dermatol Res., 304 (9): 755-64.

Carola A, Tito A, Bimonte M, Mustilli AC, Cucchiara M, Monoli I, Hill J, Apone F, Colucci MG.
Liposoluble Extracts of Vitis Vinifera Grape Marc and Cell Cultures with Synergistic Anti-ageing Effects.
HPC Today, vol. 7 nr. 3 July/September 2012.

2011

Quintavalle C, Brenca M, De Micco F, Fiore D, Romano S, Romano MF, Apone F, Bianco A, Zabatta MA, Troncone G, Briguori C, Condorelli G.
In Vivo and in Vitro Assessment of Pathways Involved in Contrast Media-induced Renal Cells Apoptosis.

Cell Death Dis., May 12; 2: e 155.

Tito A, Carola A, Bimonte M, Barbulova A, Arciello S, De Laurentiis F, Monoli I, Hill J, Gibertoni S, Colucci MG & Apone F.
A Tomato Stem Cell Extract, Containing Antioxidant Compounds and Metal Chelating Factors, Protects Skin Cells from Heavy Metal Induced Damages.

Int. J. Cosmet. Sci., 33(6): 543-552.

Bimonte M, Tito A, Carola A, Barbulova A, Monoli I, Cucchiara M, Hill J, Colucci MG & Apone F.
A New Active Extract Obtained from Coffea bengalensis Stem Cells Acts on Different Skin Cell Types Attenuating Signs of Ageing.
Cosmetics & Toiletries, September 2011, vol. 126 (9): 644-650.

2010

Barbulova A, Tito A, Carola A, Bimonte M, De Laurentiis F, D’ambrosio P, Apone F and Colucci MG.
Raspberry Stem Cell Extract to Protect Skin from Inflammation and Oxidative Stress.
Cosmetics & Toiletries, 125(7): 38-47.

2009

Apone F, Tito A, Carola A, Arciello S, Tortora A, Filippini L, Monoli I, Cucchiara M, Gibertoni S, Chrispeels MJ, Colucci MG.
A Mixture of Peptides and Sugars Derived from Plant Cell Walls Increases Plant Defense Responses to Stress and Attenuates Ageing- associated Molecular Changes in Cultured Skin Cells.

J. Biotechnol., 145(4): 367-376.

2007

Apone F, Arciello S, Colucci MG, Filippini L, Portoso D.
An In-depth Investigation to Provide Scientific Bases to the Biostimulant Activity.

Fert. Agrorum, 1 (1): 55-63.

2003

Apone F, Alyeshmerni N, Wiens K, Chalmers D, Chrispeels JM & Colucci MG.
The G-protein Coupled Receptor GCR1 Regulates DNA Synthesis through Activation of Phosphatidylinisitol-specific Phospholipase C (PI-PLC).

Plant Physiology, 133 (2): 571-9.

2002

Colucci MG, Apone F, Alyeshmerni N, Chalmers D & Chrispeels M.
GCR1, the Putative Arabidopsis G Protein-coupled Receptor Gene is Cell Cycle-regulated, and its Overexpression Abolishes Seed Dormancy and Shorten Time to Flowering.

Proc. Nat. Acad. Sci., 99 (7): 4736-4741.

2000

Moore JG, Fuchs CA, Hata YS, Hicklin DJ, Colucci MG, Chrispeels MJ, Feldman M.
A New Lectin in Red Kidney Beans Called PvFRIL Stimulates Proliferation of NIH 3T3 Cellsexpressing the Flt3 Receptor.

Biochim Biophys Acta 26;1475(3): 216-224.

1999

Colucci MG, Moore JG, Feldman M & Chrispeels MJ.
cDNA Cloning of FRIL, a Mannose Binding Lectin from Dolichos lablab, that Preserves Hematopoietic Progenitors in Suspension Culture.
Proc. Natl. Acad. Sci. USA (2): 646-650.

patents

publications

2021

Ceccacci S, De Lucia A, Tito A, Tortora A, Falanga D, Arciello S, Ausanio G, Di Cicco C, Monti MC and Apone F.
An Oenothera biennia Cell Cultures Extract Endowed with Skin Anti-Ageing Activity Improves Cell Mechanical Properties.
Metabolites 2021, 11, 527. https://doi.org/10.3390/metabo11080527.

Apone F.
Uses and Properties of Bioactive Peptides in Skin Care.
HPC Today, vol. 16 (3), 2021.

Tito A, Colantuono A, Pirone L, Pedone E, Intartaglia D, Giamundo G, Conte I, Vitaglione P, Apone F.
Pomegranate Peel Extract as an Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 Receptor (in vitro): A Promising Source of Novel Antiviral Drugs.
Front Chem. 2021 Apr 28;9:638187.

Dini I, Falanga D, Di Lorenzo R, Tito A, Carotenuto G , Zappelli C, Grumetto L , Sacchi A, Laneri S, Apone F.
An Extract from Ficus carica Cell Cultures Works as an Anti-Stress Ingredient for the Skin.
Antioxidants2021, 10, 515. https://doi.org/10.3390/antiox10040515.

Tortora A, Bimonte M, Tito A, Zappelli C, Apone F.
Soothing Moves: Cannabis sativa Cell Culture Alleviates Inflammation. 
Cosmetic & Toiletries, Jan 2021, vol. 136, n. 1, 34-39.

2020

Laneri S, Dini I, Tito A, Di Lorenzo R, Bimonte M, Tortora A, Zappelli C, Angelillo M, Bernardi A, Sacchi A, Colucci MG and Apone F.
Plant Cell Culture Extract of Cirsium eriophorum with Skin Pore Refiner Activity by Modulating Sebum Production and Inflammatory Response.
Phytother Res. 2020; 10.1002/ptr.6832. doi: 10.1002/ptr.6832.

Tito A, Tortora A, De Lucia A, Zappelli C, Colucci MG and Apone F.
A Peptide Preparation from Scabiosa arvensis Cell Cultures Increases Skin Compactness by Stimulating Collagen XVII and Insulin-like Growth Factor.
The Proceedings of the 26th IFSCC Congress 2020, Yokohama.

Tito A, Colantuono A, Pirone L, Pedone E, Intartaglia D, Giamundo G, Conte I, Vitaglione P and Apone F.
A Pomegranate Peel Extract as Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 (in vitro): A Promising Source of Novel Antiviral Drugs.
bioRxiv December 2020, https://doi.org/10.1101/2020.12.01.406116.

Apone F, Tito A, Arciello S, Carotenuto G and Colucci MG.
Plant Tissue Cultures as Sources of Ingredients for Skin Care Applications.
Annual Plant Reviews 2020, 3: 135-150. 

Tito A, Minale M, Riccio S, Grieco F, Colucci MG and Apone F.
A Triticum vulgare Extract Exhibits Regenerating Activity during the Wound Healing Process.
Clin Cosm & Invest Dermatol 2020, 13: 21-30.

Tito A, Zappelli C, Angelillo M, Colucci MG and Apone F.
A New Ingredient from Rosa rugosa Tissue Cultures Delays Skin Aging by Promoting Mitochondrial Functions.
Personal Care Europe 2020, April 131-137.

2019

Tito A, Carola A, Bertelli G, Rando P, Nohynek L, Oksman-Caldentey KM, Rischer H, Zappelli C, Colucci MG, Apone F.
A Rubus arcticus derived ingredient stimulates immune defence and reduces inflammation in skin cells by promoting microbiota balance.
The Proceedings of the 25th IFSCC Conference 2019, Milan.

Bimonte M, Carola A, Barbulova A, Zappelli C, Angelillo M, Cucchiara M, Apone F and Colucci MG.
Aubergine mutes TRPV1 and boosts TRPV-3 and TRPV-4 to reinforce and comfort skin (2019).
Cosmetics & Toiletries, 134, n. 9, 50-61.

Palmieri G, Arciello S, Bimonte M, Carola A, Tito A, Gogliettino M, Cocca E, Fusco C, Balestrieri M, Colucci MG, Apone F.
The extraordinary resistance to UV radiations of a manganese Superoxide Dismutase of Deinococcus radiodurans offers promising potentialities in skin care applications.
J Biotechnol. 2019, 302: 101-111.

Apone F, Barbulova A, Colucci MG.
Plant and Microalgae Derived Peptides Are Advantageously Employed as Bioactive Compounds in Cosmetics.
Front. In Plant Sci., 12 June 2019 doi: 10.3389/fpls.2019.00756

Tito A, Barbulova A, Zappelli C, Leone M, Ruvo M, Mercurio FA, Chambery A, Russo R, Colucci MG & Apone F.
The Growth Differentiation Factor 11 is involved in skin fibroblast ageing and is induced by a preparation of peptides and sugars derived from plant cell cultures.
Mol Biotechnol. 2019 Mar;61(3):209-220.

2018

Guerriero G, Berni R, Muñoz-Sanchez JA, Apone F, Abdel-Salam EM, Qahtan AA, Alatar AA, Cantini C, Cai G, Hausman JF, Siddiqui KS, Hernández-Sotomayor SMT, Faisal M.
Production of Plant Secondary Metabolites: Examples, Tips and Suggestions for Biotechnologists.
Genes (Basel). 2018 Jun 20; 9(6).

Bimonte M, Carola A, Tito A, Barbulova A, De Lucia A, Del Piaz F, Apone F & Colucci MG.
Plant cell cultures of Daphne odora produce compounds that help fighting cold stress in the skin.
Cosmetics & Toiletries, 133, n.1, 34-51.

De Lucia A, Zappelli C, Angelillo M, Langellotti AL, Fogliano V, Cucchiara M, Colucci MG, Apone F.
A novel biotechnological active ingredient, derived from the microalga Spirulina, increases hydration and reduces osmotic stress in skin cells.

H&PC Today – Household and Personal Care Today – vol. 13(4) July/August 2018.

D’Antuono I, Carola A,  Sena LM, Linsalata V, Cardinali A, Logrieco AF, Colucci MG and Apone F.
Artichoke polyphenols produce skin anti-age effects by improving endothelial cell integrity and functionality.
Molecules 2018, 23, 2729; doi:10.3390/molecules23112729.

Apone F, Zappelli C, Angelillo M & Colucci MG.
Biotechnology research to obtain safe, effective and sustainable ingredients for Cosmetics (in polish).
Chem & Business, 4/2018: 76-81.

2017

Sandomenico A, Severino V, Apone F, De Lucia A, Caporale A, Dotia N, Russo A, Russo R, Rega C, Del Giacco T, Falcigno L, Ruvo M, Chambery A.
Trifluoroacetylated tyrosine-rich D-tetrapeptides have potentantioxidant activity.
Peptides, 89: 50–59.

Apone F, Barbulova A, Zappelli C, Colucci MG.
Green biotechnology in cosmetics: using plant cell cultures as sources of active ingredients.
HPC Today, vol. 12 (3), May/June 2017.

Sena LM, Zappelli C, Apone F, Barbulova A, Tito A, Leone A, Oliviero T, Ferracane R, Fogliano V, Colucci MG.
Brassica rapa hairy root extracts promote skin depigmentation by modulating melanin production and distribution.
J Cosmet Dermatol.1–12.

Squillaci G, Apone F, Sena LM, Carola A, Tito A, Bimonte M, De Lucia A, Colucci MG, LA Cara F, Morena A.
Chestnut (Castanea sativa Mill.) industrial wastes as a valued bioresource for the production of active ingredients.
Process Biochemistry, http://dx.doi.org/10.1016/j.procbio.2017.09.017.

Di Martino O, Tito A, De Lucia A, Cimmino A, Cicotti F, Apone F, Colucci MG and Calabrò V.
Hibiscus syriacus Extract from an Established Cell Culture Stimulates Skin Wound Healing.
BioMed Res Inter, Article ID 7932019, 9 pages, https://doi.org/10.1155/2017/7932019.

2016

Imparato G, Casale C, Scaramella S, UrciuoloF, Bimonte M, Apone F, Colucci MG and Netti PA.
A novel engineered dermis for in vitro photodamage research.
J Tissue Eng Regen Med. 2016 Feb 8.

Bimonte M, De Lucia A, Carola A, Tito A, Buono S, Langellotti AL, Fogliano V, Colucci MG and Apone F.
Galdieria sulphuraria Relieves Oily and Seborrheic Skin By Inhibiting the 5-α Reductase Expression in Skin Cells and Reducing Sebum Production In Vivo.

Trichology and Cosmetology. Volume 1, tissue 1.

Rogato A, Valkov VT, Alves LM, Apone F, Colucci MG, Chiurazzi M.
Down-regulated Lotus japonicus GCR1 plants exhibit nodulation signalling pathways alteration.
Plant Sci., 247: 71-82.

Zappelli C, Barbulova A, Apone F, Colucci MG.
Effective Active ingredients obtained through Biotechnology.
Cosmetics, 3, 39.

Zappelli C, Ciccotti F, Tito A, Carola A, De Lucia A, Sena LM, Tortora A, Bimonte M, Cucchiara M, Apone F, Colucci MG.
Perking Up Skin: Green Coffee Promotes Barrier Recovery, Turn Over and Lightening.
Cosmetics & Toiletries, 132, n.1, 24-36.

2015

Barbulova A, Apone F & Colucci MG.
New Trends in Cosmetics: By-Products of Plant Origin and Their Potential Use as Cosmetic Active Ingredients.
Cosmetics, 2, 82-92.

Tito A, Bimonte M, Carola A, De Lucia A, Barbulova A, Tortora A, Colucci MG & Apone F.
An oil-soluble extract of Rubus idaeus cells enhances hydration and water homeostasis in skin cells.

Int. J. Cosmet. Sci., 2015 May 4. doi: 10.1111/ics.12236.

2014

Barbulova A, Apone F & Colucci MG.
Plant Cell Cultures as Source of Cosmetic Active Ingredients.

Cosmetics, 1, 94-104.A.

Apone F, Ruggiero A, Tortora A, Tito A, Grimaldi MR, Arciello S, Andrenacci D, Di Lelio I & Colucci MG.
Targeting the diuretic hormone receptor to control the cotton leafworm, Spodoptera littoralis.

Journal of Insect Science, Vol. 14, 87, 1-16.

Bimonte M, Tito A, Carola A, Barbulova A, Hill J, Cucchiara M, Apone F & Colucci MG.
Dolichos cell culture extract for protection against UV damage.
Cosmetics & Toiletries, 129, 46-56.

2012

Tortora A, Arciello S, Colucci MG, Apone F.
Identification of Novel Compounds or Mixtures, Activating Common Defense Responses to Abiotic Stress both in Plants and Mammalian Skin Cells.

Advances in Medicine and Biology, vol. 49, pp. 47-67.

Buono S, Langellotti A, Martello A, Bimonte M, Tito A, Carola A, Apone F, Colucci MG, Fogliano V.
Biological Activities of Dermatological Interest by the Water Extract of the Microalga Botryococcus braunii.

Arch Dermatol Res., 304 (9): 755-64.

Carola A, Tito A, Bimonte M, Mustilli AC, Cucchiara M, Monoli I, Hill J, Apone F, Colucci MG.
Liposoluble Extracts of Vitis Vinifera Grape Marc and Cell Cultures with Synergistic Anti-ageing Effects.
HPC Today, vol. 7 nr. 3 July/September 2012.

2011

Quintavalle C, Brenca M, De Micco F, Fiore D, Romano S, Romano MF, Apone F, Bianco A, Zabatta MA, Troncone G, Briguori C, Condorelli G.
In Vivo and in Vitro Assessment of Pathways Involved in Contrast Media-induced Renal Cells Apoptosis.

Cell Death Dis., May 12; 2: e 155.

Tito A, Carola A, Bimonte M, Barbulova A, Arciello S, De Laurentiis F, Monoli I, Hill J, Gibertoni S, Colucci MG & Apone F.
A Tomato Stem Cell Extract, Containing Antioxidant Compounds and Metal Chelating Factors, Protects Skin Cells from Heavy Metal Induced Damages.

Int. J. Cosmet. Sci., 33(6): 543-552.

Bimonte M, Tito A, Carola A, Barbulova A, Monoli I, Cucchiara M, Hill J, Colucci MG & Apone F.
A New Active Extract Obtained from Coffea bengalensis Stem Cells Acts on Different Skin Cell Types Attenuating Signs of Ageing.
Cosmetics & Toiletries, September 2011, vol. 126 (9): 644-650.

2010

Barbulova A, Tito A, Carola A, Bimonte M, De Laurentiis F, D’ambrosio P, Apone F and Colucci MG.
Raspberry Stem Cell Extract to Protect Skin from Inflammation and Oxidative Stress.
Cosmetics & Toiletries, 125(7): 38-47.

2009

Apone F, Tito A, Carola A, Arciello S, Tortora A, Filippini L, Monoli I, Cucchiara M, Gibertoni S, Chrispeels MJ, Colucci MG.
A Mixture of Peptides and Sugars Derived from Plant Cell Walls Increases Plant Defense Responses to Stress and Attenuates Ageing- associated Molecular Changes in Cultured Skin Cells.

J. Biotechnol., 145(4): 367-376.

2007

Apone F, Arciello S, Colucci MG, Filippini L, Portoso D.
An In-depth Investigation to Provide Scientific Bases to the Biostimulant Activity.

Fert. Agrorum, 1 (1): 55-63.

2003

Apone F, Alyeshmerni N, Wiens K, Chalmers D, Chrispeels JM & Colucci MG.
The G-protein Coupled Receptor GCR1 Regulates DNA Synthesis through Activation of Phosphatidylinisitol-specific Phospholipase C (PI-PLC).

Plant Physiology, 133 (2): 571-9.

2002

Colucci MG, Apone F, Alyeshmerni N, Chalmers D & Chrispeels M.
GCR1, the Putative Arabidopsis G Protein-coupled Receptor Gene is Cell Cycle-regulated, and its Overexpression Abolishes Seed Dormancy and Shorten Time to Flowering.

Proc. Nat. Acad. Sci., 99 (7): 4736-4741.

2000

Moore JG, Fuchs CA, Hata YS, Hicklin DJ, Colucci MG, Chrispeels MJ, Feldman M.
A New Lectin in Red Kidney Beans Called PvFRIL Stimulates Proliferation of NIH 3T3 Cellsexpressing the Flt3 Receptor.

Biochim Biophys Acta 26;1475(3): 216-224.

1999

Colucci MG, Moore JG, Feldman M & Chrispeels MJ.
cDNA Cloning of FRIL, a Mannose Binding Lectin from Dolichos lablab, that Preserves Hematopoietic Progenitors in Suspension Culture.
Proc. Natl. Acad. Sci. USA (2): 646-650.

patents